Vasoptic Medical Inc. is a medical device company developing and commercializing high-quality, cost-effective products for the non invasive, dynamic assessment of retinal blood flow and vascular status. Vasoptic Medical has developed a low-cost, portable, noninvasive retinal imaging instrument (the XyCAM), which can complement fundus photographs with retinal blood flow information obtained at high spatio-temporal resolution without the introduction of any dyes. This handheld retinal imager has the potential to help detect a number of clinical conditions, including diabetic retinopathy (DR), glaucoma, and age-related macular degeneration. Early detection can often prevent vision loss. The XyCAM device is being designed to detect these conditions inn their earliest stages to help healthcare providers manage and prevent DR and glaucoma progression through a convenient, low-cost, minimally invasive procedure.

Abilis LS is developing a non-invasive, accurate, sensitive and specific diagnostic staging test for bladder cancer. The company’s bladder cancer test has the potential to be quickly incorporated into the routine urinalysis of all adult male and female patients with hematuria, as well as for the surveillance of recurrence and progression in patients with a history of non-muscle, invasive bladder cancer (NMIBC).

Mastix LLC develops and manufactures niche healthcare products such as tableted chewing gum, chewable tablets and lozenges. Mastix is one of only a few companies in the world (and the only one in the U.S.) that has the ability to make tableted chewing gum products at room temperature versus the traditional high-heat process, which degrades active ingredients and reduces their efficacy. Mastix can also create custom formulations.

‍

38° North LLC is a fully integrated oyster grow-out company, with activities spanning nursery operations, grow-out, packaging, marketing and the shipping of oysters throughout the United States. While modest in size, 38 North is currently one of the largest producers of aquaculture oysters in Maryland.

BondTrue has developed a patented medical device that automates the process of surgical incisions and closures. The result is a fast, precise surgical wound that can be rapidly approximated and repaired. This significantly reduces surgical times and ensures excellent wound repair. Precise wound repair is associated with reduced scarring and decreased wound complications, including surgical wound infections.

ATP-MD LLC is the Maryland operating affiliate of Agri-Tech Producers LLC (ATP), a South Carolina-based, tech holding company. ATP has given ATP-MD exclusive rights to use ATP’s technologies in Maryland. ATP has a patent-pending Combined Remediation Biomass and Bio-Product Production (CRBBP) Process, along with a license to patented torrefaction technology developed by NC State University (NCSU).

ATP’s CRBBP process multi-tasks bio-crops and their resulting biomass to remediate soils and waters and to then make environmentally beneficial bio-products.

ATP’s torrefaction process is a form of mild pyrolysis, which heats biomass (animal, plant and woody material), in the absence of oxygen, changing it into a carbon-rich, energy-dense, dry and hydrophobic material that is easily ground into fine particles.

Crab Machinery is an engineering design, production and sales company dedicated to developing crab meat processing machines for crab meat processors.

3i Diagnostics provides technology that enables physicians to identify infectious microbes within an hour, while leaving them intact for further testing. Physicians can then prescribe the right life-saving medications quickly, which reduces the cost of care and prevents the overprescribing that hastens the spread of drug-resistant bacteria.

The Low Impact Development Design Group, or LIDDG, manufactures and distributes two storm water best management practice (BMP) product lines.

LIDMIX is a media that is designed to treat the heavy metals zinc (Zn), copper (Cu), and lead (Pb), as well as other metals and non-point source runoff stormwater pollutants. The media can be used in existing media-based stormwater treatment devices, such as cartridges and filters, to enhance their performance.

The other product is LIDMAT™, for which LIDMIX™ media is inserted into a geotextile mat that is formed into modules that can be attached to each other to treat sheet flow or attached to a storm drain structure. A biodegradable version of the LIDMAT™ is also available. It can be planted with hyper accumulators, which will enhance the capture of pollutants.

Manta Biofuel is a producer of renewable algal crude oil that is cost-competitive with traditional crude oil. The company employs technological advantages in a three-step process to produce crude oil from algae. The first is growing algae. Manta can convert algae from any source, leaving options open from farming to collecting natural blooms. For the second step, harvesting the algae, Manta uses a proprietary magnetic harvester that efficiently collects and concentrates algae. The company then converts the algae to crude oil through hydrothermal liquefaction (HTL).

Whisker Labs has built an energy management platform, Connected SavingsSM, which is an intelligent demand side management (IDSM) system that ties homes with utilities, big weather data and analytics to save energy—for customers, utilities and retail energy providers. The solution combines connected thermostats with proprietary weather information and thermodynamic models, developed in part with the University of Maryland, that predict how homes will respond to changing weather conditions, thus correlating energy usage to weather. Homes can then be intelligently precooled and setback, keeping customers comfortable while shifting loads for utilities during peak load events (DR events).

HY-TEK Bio is an early stage company developing a patent-pending system to remove carbon dioxide and other harmful greenhouse gases from smoke stack flue gas using a unique strain of algae while producing valuable byproducts from the algae. The company’s system mitigates greenhouse gas from flue gases by injecting the flue gas into a tank full of a unique strain of algae. The tank is a patent-pending, closed bioreactor produced in-house from a lamination of Mylar and Kevlar. This patent-pending construct allows the bioreactors to be produced inexpensively while being extremely light weight. In addition, patent-pending LED Grow Lights are used along with a nutrient developed in-house, made from fresh chicken manure and a blend of other proprietary components.

The algae feeds on the CO2 and NOx in the flue gas, as well as on the nutrient. CO2 consumption is enhanced through the use of proprietary LED Grow Light technology, yielding minimal greenhouse gas emissions and high yields of high-value algal biomass. The process produces little to no CO2 or NOx emissions, while enhancing the lipid-oil production in the algae as well as a by-product of Lutein-Zeaxanthin, an ultra-antioxidant that is in high demand in the market place. The algal biomass can be sold to brokers, who place the biomass into markets that produce Lutein-Zeaxanthin-based products, bio-plastics, skin care products, cosmetic and paint thickeners, additives for human and animal food products, and biofuel.

CoapTech seeks to bring a series of breakthrough medical devices to worldwide markets, leveraging a patent-pending, disruptive technology called Coaptive Ultrasound. The company’s CoapTech Carrier™ is a novel platform technology combining magnetic attraction for device placement guidance and low-cost, point-of-care ultrasound for visual feedback in diagnostic, interventional and therapeutic procedures.

CoapTech is commercializing a kit that will enable clinicians to perform a novel procedural method called Percutaneous Ultrasound Gastrostomy (PUG) for the placement of semi-permanent feeding tubes in the stomach. PUG improves on Percutaneous Endoscopic Gastrostomy (PEG), the current standard of care for feeding tube placement. The company believes that PUG is a safer, simpler, and less expensive method for placing feeding tubes.

Microsphere Material Solutions LLC is a producer of ultra-high-strength, low-weight materials that provide game-changing capabilities for many applications. Microsphere Material Solutions engages in both the small batch production and research and development of amorphous glass foams for cutting-edge applications. The extraordinary compressive strength-to-weight ratio of amorphous glass foam materials allows for the exploration of new form factors and enhanced capabilities in a wide variety of markets.

Millennium Engineering and Integration Company is an employee-owned small business with systems engineering and integration capability in the space, defense, cyber, intelligence, aviation and healthcare markets. The company provides solutions to both the U.S. Government and commercial sectors, solving engineering challenges in satellites, missiles, aircraft, cyber, space resiliency and beyond.

Tarsier Optics is developing a novel camera system that provides ‘panoramic’ photographs that can resolve micron-level structures at distances of ten miles, independent of the optics. Ultimately, cell phone-like lenses can be used, creating highvalue products in the defense and commercial remote sensing markets, as well as highend consumer segments. Tarsier’s prototype uses “photon counting” and “coincidence counting” measurement devices to capture the data.

Sonavex Inc. is a medical device company spun out of Johns Hopkins. The company is dedicated to providing novel ultrasound solutions to visualize and quantify critical data for improved outcomes and reduce costs in new surgical applications. Sonavex developed EchoSure to detect blood clots after surgery to prevent catastrophic surgical failures.