38° North LLC is a fully integrated oyster grow-out company, with activities spanning nursery operations, grow-out, packaging, marketing and the shipping of oysters throughout the United States. While modest in size, 38 North is currently one of the largest producers of aquaculture oysters in Maryland.

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N5 Sensors, a University of Maryland spin-off founded by UMD Research Scientist Abhishek Motayed, is commercializing a new generation of chip-scale chemical sensors that can detect harmful chemicals mixed in air, such as industrial chemicals, automobile exhausts, cigarette smoke, and pollutants released from paints, cleaners, pesticides and other products. These new sensors, built using the same fabrication processes that are commonly used for silicon computer chips, are small and accurate, with the capability to detect multiple gases at the same time. N5 is working to develop arrays of multi analyte sensors on a single chip, which can be integrated with smart phones, allowing industrial workers, first-responders, and soldiers to assess the dangers of their surroundings rapidly and accurately in real-time using their smart phones.

Vasoptic Medical Inc. is a medical device company developing and commercializing high-quality, cost-effective products for the non invasive, dynamic assessment of retinal blood flow and vascular status. Vasoptic Medical has developed a low-cost, portable, noninvasive retinal imaging instrument (the XyCAM), which can complement fundus photographs with retinal blood flow information obtained at high spatio-temporal resolution without the introduction of any dyes. This handheld retinal imager has the potential to help detect a number of clinical conditions, including diabetic retinopathy (DR), glaucoma, and age-related macular degeneration. Early detection can often prevent vision loss. The XyCAM device is being designed to detect these conditions inn their earliest stages to help healthcare providers manage and prevent DR and glaucoma progression through a convenient, low-cost, minimally invasive procedure.

Belloso Motor Company has developed a Dual-Engine Technology System that provides significantly improved fuel economy without sacrificing performance or requiring expensive and complex hybrid technology.